Hayes principles and methods of toxicology has long been established as a reliable reference to the concepts methodologies and assessments integral to toxicology the new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. Emphasizing the cornerstones of toxicology people differ dose matters and things change the . Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity the determination of safe dosage forms the base and focus of modern toxicology in order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanis. Extensively revised and updated with four new chapters and an expanded glossary this fifth edition of the classic text principles and methods of toxicology provides comprehensive coverage in a manageable and accessible format new topics include toxicopanomics plant and animal poisons information resources and non animal testing alternatives
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